Promega is committed to excellence in technologies and compound profiling services to assess key processes in Targeted Protein Degradation and Induced Proximity mechanisms. From assessing protein degradation in real time, to understanding compound binding and permeability, to ternary complex formation and more. Our CRIPSR HiBiT content covers hundreds of pre-built targets. Novel software analysis tools allow for the determination of target protein degradation rates, DC50 potency values, recovery profiles and more.
Biortus is a structure-based drug discovery CRO with a mature protein focused lead generation platform including modular services in protein production, assay development, fragment screening, and structure determination in microED, CryoEM, and X-ray crystallography.We’ve solved structures of some ternary degradation complexes including VHL and CRBN based PROTACs. Our newest Boston site is available for 2-way sample shipment and serves as the headquarters for our off-the-shelf Protein Catalogue which includes DUBS, E3 ligases, and more.
BMG LABTECH is a German-based company that focuses exclusively on microplate readers and our technological innovations have made us a leader in the field. Our PHERAstar FSX is the gold standard for all HTS and drug discovery applications with unparalleled speed and sensitivity. We can help you get the best possible data in the most challenging assays, such as FP, TR-FRET and NanoBRET.