Screening Rationally Designed MGD Libraries to Unravel Degradable Proteins
Time: 10:00 am
day: Day One
Details:
- MGDs bind E3 ubiquitin ligases and create neomorphic surface for novel PPI
- MGD libraries are rationally designed with chemical diversity and drug-like properties.
- Phenotypic, proteomic and reporter screening strategies are used to identify degradable proteins by the library compounds
