Screening Rationally Designed MGD Libraries to Unravel Degradable Proteins

Time: 10:00 am
day: Day One


  • MGDs bind E3 ubiquitin ligases and create neomorphic surface for novel PPI
  • MGD libraries are rationally designed with chemical diversity and drug-like properties.
  • Phenotypic, proteomic and reporter screening strategies are used to identify degradable proteins by the library compounds