The Plexium Platform Expands the Repertory of E3 Ligases in TPD Drug Discovery

Time: 9:00 am
day: Day Two


• Overview of the Plexium screening platform: Multiple detection readouts to identify monovalent degrader or molecular glue effects in cells
• Case study of new E3 ligase discovery using monovalent degrader identified in protein degradation screening
• E3 ligase redirection using RNAseq screening