Darshan Sappal

Darshan Sappal

Company: Foghorn Therapeutics

Job title: Principal Scientist


Assay Development Towards the Optimization of Effective Degraders 4:00 pm

• Targeted protein degradation (TPD) is an emerging novel therapeutic modality with the potential to tackle traditionally difficult to target (undruggable) disease-causing proteins • Highly efficacious degraders (PROTAC) induce rapid and selective degradation of the POI with high potency (DC50) and high maximal degradation (Dmax). To optimize such parameters a sensitive bioluminescence protein quantitation system…Read more

day: Day One

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